Home » Cholesterol and Presynaptic Glutamate Transport in the Brain by Tatiana Borisova
Cholesterol and Presynaptic Glutamate Transport in the Brain Tatiana Borisova

Cholesterol and Presynaptic Glutamate Transport in the Brain

Tatiana Borisova

Published November 19th 2013
ISBN : 9781299859074
ebook
90 pages
Enter the sum

 About the Book 

Glutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number ofneurological and neurodegenerative disorders. Appropriate levels of cholesterol are very important for the properMoreGlutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number ofneurological and neurodegenerative disorders. Appropriate levels of cholesterol are very important for the proper functioning of glutamate transport whileunbalanced levels ofcholesterol have been implicated in the pathogenesis of disorders such as stroke, ischemia, traumatic brain injury, and neurotoxicity.In the proposed book, the author presents data from the literature and from her own lab to address the extent to and way in which membrane cholesterol modulates presynaptic glutamate transport and whether lowering the level of cholesterol available can offer some neuroprotective benefits.?